ZeoBindTM assists the body in removing heavy metals such as lead, mercury, cadmium, and arsenic (1). It can also support removal of other toxins including herbicides (2), pesticides (3), radionuclides (4), mycotoxins (4), and pre-viral components (5). ZeoBindTM is made from a naturally occurring mineral known as clinoptilolite, which is a particular type of crystalline aluminosilicate in a family of compounds known as zeolites. Clinoptilolite is formed when volcanic molten lava comes in contact with seawater. The result is a 3-dimensional honeycomb-like molecular structure with a negative charge that is unique among minerals in nature. Most heavy metals and other xenobiotics have a positive charge. They are attracted to clinoptilolite’s negative charge and an ion-exchange is readily performed (5). The toxic substances essentially become captive within the porous, sieve-like architecture of ZeoBindTM and are then shuttled out of the body via the feces or urine.
ZeoBindTM’s beneficial detoxification takes place primarily in the gut and in the enterohepatic circulatory system. The natural adsorptive and alkalizing properties of clinoptilolite support gastrointestinal health, and can be helpful in the prevention of dyspepsia, diarrhea, and ulcers, to normalize pH, adsorb bile acids and glucose, as well as remove potentially irritating and dangerous heavy metals and toxins (6). Research has also found that clinoptilolite demonstrates an antiproliferative effect on tumor cell growth in mice (7), can stimulate the immune system, and act as an antioxidant (7,8). Clinoptilolite and other similar zeolites have been used throughout history for a variety of purposes. In the construction industry they provide a lightweight, easy-to-cut material for building (4). They have been effectively used in water purification systems (4,9). They can serve as a natural deodorizer (4). They have been added to livestock feed to prevent the growth of molds and animal exposure to aflatoxins, and were found to have a positive effect on animal health (4). Clinoptilolite was also used to clean up radionuclides from nuclear waste fallout from the environment and in humans after the Chernobyl, Three Mile Island, and Fukushima disasters (4,10).
Medical research is finding increased usefulness for clinoptilolite, as well as modified forms of the mineral, including: to deliver drugs to specific locations in the body, anti-acne support (11), to speed wound healing, to filter out ammonia in kidney-dialysis units (6), and as a beneficial adjuvant in anticancer therapy (6,7,12), and more. Experiments have shown that dietary use of clinoptilolite for removal of heavy metals does not decrease important electrolytes in the body to clinically dangerous levels as some types of chelation therapy can (1,13) and has little or no side effects (14). This valuable ancient mineral is carefully mined, cleaned, dried, and prepared into a fine powder, using a proprietary process, for use in BioPure’s ZeoBindTM. The product is free from fillers, additives and binding agents.
(1) Flowers JL, Stewart AL, Deitsch EJ. Clinical evidence supporting the use of an activated clinoptilolite suspension as an agent to increase urinary excretion of toxic heavy metals. Nutrition and Dietary Supplements. November 2009, Volume 2009:1, pg 11-18.
(2) Mumpton, FA. Using Zeolites in Agriculture. Chapter VIII. Department of the Earth Sciences State University College Brockport, NY 14420.
(3) Jovanović V, Dondur V, Damjanović L, Jordanov G, and Daković A. Adsorption of pesticides on functionalized zeolites. Zeolite ’06 (Proceedings of the 7th International Conference on the Occurrence, Properties and Utilization of Natural Zeolites) Socorro, New Mexico USA. 16–21 July 2006.
(4) Mumpton FA. La roca magica: Uses of natural zeolites in agriculture and industry. Proceedings of the National Academy of Sciences of the United States of America. 1999. Vol. 96 no. 7. Pg 3463–3470
(5) Jurkić LM, Cepanec I, Pavelić SK and Pavelić K. Biological and therapeutic effects of ortho-silicic acid and some ortho-silicic acid-releasing compounds: New perspectives for therapy. Nutrition & Metabolism 2013, 10:2.
(6) Dlugopolska, K., Ruman, T., Pogocki, D. and Danilczuk, M. Medical Applications of Molecular Sieves. Journal of Polish Chemical Society. 2009 Vol. 63(11-12):pp.1073-1088.
(7) Pavelić K, Hadzija M, Bedrica L, Pavelić J, Dikić I, Katić M, Kralj M, Bosnar MH, Kapitanović S, Poljak-Blazi M, Krizanac S, Stojković R, Jurin M, Subotić B, Colić M. Natural zeolite clinoptilolite: new adjuvant in anticancer therapy. J Mol Med (Berl). 2001;78(12):708-20.
(8) Ivkovic S, Deutsch U, Silberbach A, Walraph E, Mannel M. Dietary supplementation with the tribomechanically activated zeolite clinoptilolite in immunodeficiency: Effects on the immune system. Advances in Therapy. March–April 2004, Volume 21, Issue 2, pp 135-147.
(9) Buasri A, et al. Use of Natural Clinoptilolite for the Removal of Lead (II) from Wastewater in Batch Experiment. Chiang Mai J. Sci. 2008; 35(3) : 447-456.
(11) G. Cerri M. de’ Gennaro M.C. Bonferoni C. Caramella. Zeolites in biomedical application: Zn-exchanged clinoptilolite-rich rock as active carrier for antibiotics in anti-acne topical therapy. Applied Clay Science. 2004, 27:3-4, pp 141-150.
(12) Katic M, Bosnjak B, Gall-Troselj K, Dikic I, Pavelic K. A clinoptilolite effect on cell media and the consequent effects on tumor cells in vitro. Front Biosci. 2006 May 1;11:1722-32.
(13) Karampahtsis E. Zeolite: Investigation of the Effectiveness and Safety as an Oral Chelating Agent for Heavy Metals. A comparison between different commercially available preparations. 2012.
(14) Sampson, R. Application for the Approval of Clinoptilolite. Regulation (EC) No.258/97 of the European Parliament and of the Council of 27th January 1997 concerning novel foods and novel food ingredients. http://www.food.gov.uk/multimedia/pdfs/clinoptilolite.pdf. 3/28/14