Liposomal Calendula 2oz

2oz. (60mL)

66- 3000 X 3000

$50.00

SKU: 590 Category:

BioPure offers two types of Calenduala officinalis extract—a tincture made in 70% organic ethanol and purified water, and Liposomal Calendula, a form in which the liquid extract of the herb has been blended with natural sunflower seed lecithin. The lipids in the lecithin have a close affinity to those in our own cell membranes, encouraging a greater degree of absorption and bioavailability of the beneficial effects of the Calendula extract. In addition, this liposomal delivery system serves to protect the herbal contents from degradation and breakdown from the high acidity and enzymes in the gastrointestinal tract. BioPure’s Liposomal Calendula is suspended in a solution of water, ethanol, glycerin, Vitamin E, phospholipids, and medium-chain triglycerides. Sunflower lecithin is used to avoid soy allergies.

 

Calendula officinalis is also known as “pot marigold,” an herb in the Asteraceae family. The plant should not be confused with common garden flower marigolds of the genus Tagetes. There are many species of Calendula, but C. officinalis is the only one that has a long history of traditional and modern clinical use for its medicinal and health benefits. Calendula’s bright yellow to deep orange flower petals are the primary source of its medicinal properties, although the leaves and stems are also used.

Calendula is most well-known for its inflammation modulating properties. Other health benefits include supporting the body’s natural detoxification mechanisms and deterring bacterial growth during injuries. There are records from the Civil War mentioning Calendula as a battlefield aid to stop bleeding and to reduce multiplication of invading microorganisms in wounds. This herb has also been used as far back as the Middle Ages for supporting liver function and heart health. Calendula is sometimes referred to as a “lymphogogue”, meaning it can assist in promoting the drainage and flow of lymph glands, an important aspect of detoxification. Common preparations include teas, oil infusions, alcohol extractions and tinctures, as well as direct ingestion of flower petals. It has been proven to support skin health and tissue growth. It has also been used to help calm the nervous system and skeletal muscles, and improve oral health.

The mechanisms for Calendula’s inflammation modulating property and other health benefits have been attributed to a variety of factors, including inhibition of proinflammatory cytokines and Cox-2, and subsequent prostaglandin synthesis. The herb has beneficial astringent properties, can increase the production of beneficial hyaluronic acid, fibrinogen, and stimulate angiogenesis, or new blood vessel formation. It contains potent bioactive compounds including flavonoids, terpenoids, coumarins, quinones, carotenoids, amino acids, and volatile oils. Many of these provide powerful protection against free radical damage and play key roles in Calendula’s health benefits.

Some people are known to have allergies to plants in the Asteraceae family. Use of this herb, as with any other, should be done under the supervision of a licensed healthcare practitioner.

 

References

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Efstratiou E, Hussain AD, Nigam PS, Moore JE, Ayub MA, Rao JR. Antimicrobial activity of Calendula officinalis petal extracts against Gram-negative and Gram-positive clinical pathogens. Complimentary Therapies in Clinical Practice 2012 Aug;18(3):173-6.

Fonseca YM1, Catini CD, Vicentini FT, Nomizo A, Gerlach RF, Fonseca MJ. Protective effect of Calendula officinalis extract against UVB-induced oxidative stress in skin: evaluation of reduced glutathione levels and matrix metalloproteinase secretion. J Ethnopharmacol. 2010 Feb 17;127(3):596-601.

Gazim ZC, Resende CM, Fraga SR, Svidzinski TIE, Cortez DAG. Antifungal activity of the essential oil from Calendula officinalis L. (asteraceae) growing in Brazil. Braz J Microbiol. 2008 Jan-Mar; 39(1): 61–63.

Lima MDR, Lopes AP, Martins C, Brito GAC, Carneiro VC, Goes P. The Effect of Calendula officinalis on Oxidative Stress and Bone Loss in Experimental Periodontitis. Front Physiol. 2017 Jun 28;8:440.

Muley BP, Khadabadi SS and Banarase NB. Phytochemical Constituents and Pharmacological Activities of Calendula officinalis Linn (Asteraceae): A Review. Tropical Journal of Pharmaceutical Research, October 2009; 8 (5): 455-465.

Parente LML, Lino RS Jr,  Tresvenzol LMF,  Vinaud MC, Paula JR, and Paulo NM. Wound Healing and Anti-Inflammatory Effect in Animal Models of Calendula officinalis L. Growing in Brazil. Evid Based Complement Alternat Med. Vol. 2012.

Patrick KF, Kumar S, Edwardson PA, Hutchinson JJ. Induction of vascularisation by an aqueous extract of the flowers of Calendula officinalis L. the European marigold. Phytomedicine. 1996 May;3(1):11-8.

Pazhohideh Z, Mohammadi S, Bahrami N, Mojab F, Abedi P, Maraghi E. The effect of Calendula officinalis versus metronidazole on bacterial vaginosis in women: A double-blind randomized controlled trial. J Adv Pharm Technol Res. 2018 Jan-Mar;9(1):15-19.

Pommier P, Gomez F, Sunyach MP, D’Hombres A, Carrie C, and Montbarbon X. Phase III Randomized Trial of Calendula Officinalis Compared With Trolamine for the Prevention of Acute Dermatitis During Irradiation for Breast Cancer. Journal of Clinical Oncology 2004 22:8, 1447-1453.

Preethi KC, Kuttan G, Kuttan R. Anti-inflammatory activity of flower extract of Calendula officinalis Linn. and its possible mechanism of action. Indian J Exp Biol. 2009 Feb;47(2):113-20.

Sercombe L, Veerati T, Moheimani F, Wu SY, Sood AK, Hua S. Advances and Challenges of Liposome Assisted Drug Delivery. Front Pharmacol. 2015 Dec 1;6:286.

Tanideh N, Jamshidzadeh A, Sepehrimanesh M,  Hosseinzadeh M,  Koohi-Hosseinabadi O,  Najibi A, Raam M, Daneshi S, and Asadi-Yousefabad SL. Healing Acceleration of Acetic Acid-induced Colitis by Marigold (Calendula officinalis) in Male Rats. Saudi J Gastroenterol. 2016 Jan-Feb; 22(1): 50–56.