Hyaluronic Acid (also known as Hyaluronan or HA) is a glycosaminoglycan, or GAG. Its structure is that of a long linear chain of repeating pairs of carbohydrate molecules. It is a naturally occurring gel-like substance that provides cushioning, lubrication, and flexibility in our bodies, but unfortunately, becomes less available in our older years.* The decrease of HA can lead to symptoms of aging in our skin, joints, vision, and overall health.
BioPure Healing Products offers this effective dietary supplement of Hyaluronic Acid that supports the body’s native mechanisms to help us look and feel younger longer.* BioPure’s Hyaluronic Acid liquid is offered in a 4oz bottle with a glass dropper. It is delivered orally as a liquid solution of sodium hyaluroniate (3 mg). Other ingredients are saline water and potassium sorbate.
Research & More Information
Hyaluronic Acid, also referred to as Hyaluronan or HA, is a naturally occurring viscous substance present in cells throughout the human body. The greatest concentrations of Hyaluronic Acid are found in the cartilage and synovial fluid of our joints, providing cushioning, lubrication, and flexibility; in the vitreous humor of the eye, helping to maintain resiliency and moisture; and, primarily, in the cells of our skin, providing elasticity and smoothness.*
Hyaluronic Acid is naturally produced, broken down and renewed in our bodies, but becomes less available in our older years. Many of the classic symptoms of aging such as decreased movement in our joints, a decrease in vision acuity, and the degradation of supple, wrinkle-free skin, are directly related to the decreasing content of Hyaluronic Acid in our cells.* It is now widely used in the cosmetic industry as a moisturizer and skin rejuvenator. Research studies have shown that supplemental Hyaluronic Acid can be absorbed orally and effectively utilized throughout the body and may help to lessen many of the inevitable effects of aging.*
Continued research is revealing more and more essential roles this hydrophilic gel-like chemical plays in our overall health and bodily functions. In addition to holding precious moisture and providing connective tissue structure and support, we now know that Hyaluronic Acid helps to transport nutrients and excrete wastes from our cells.* It acts as an antioxidant and helps support the immune system, too.* Hyaluronic Acid may also play a role in heart health.*
Stern, Robert. Hyaluronan catabolism: A New Metabolic Pathway. European Journal of Cell Biology 2004; Volume 83, Issue 7, 317-325.
Fraser JR, Laurent TC, Laurent UB. Hyaluronan: its nature, distribution, functions and turnover. J Intern Med.1997; Jul; 242(1): 27-33.
Holmes MW, Bayliss MT, and Muir H. Hyaluronic acid in human articular cartilage. Age-related changes in content and size. Biochem J.1988 March 1; 250(2): 435–441.
Goa KL, Benfield P. Hyaluronic acid. A review of its pharmacology and use as a surgical aid in ophthalmology, and its therapeutic potential in joint disease and wound healing. Drugs1994 Mar; 47(3):536-66.
Balogh L, Polyak A, Mathe D, Kiraly R, Thuroczy J, Terez M, Janoki G, Ting Y, Bucci LR, Schauss AG. Absorption, uptake and tissue affinity of high-molecular-weight hyaluronan after oral administration in rats and dogs. J Agric Food Chem. 2008 Nov 26; 56(22): 10582-93.
Bergnin BJ, Pierce SW, Branlage LR and Stromberg A. Oral hyaluronan gel reduces post operative tarsocrural effusion in the yearling Thoroughbred. Equine Veter. J. 2006 38(4) 375-378.
Weindla G, Schallerb M, Schäfer-Kortingc M, Kortinga HC. Hyaluronic Acid in the Treatment and Prevention of Skin Diseases: Molecular Biological, Pharmaceutical and Clinical Aspects. Skin Pharmacol Physiol2004;17:207-213
Sato H, Takahashi T, Ide H, Fukushima T, Tabata M, Sekine F, Kobayashi K, Negishi M, Niwa Y. Antioxidant activity of synovial fluid, hyaluronic acid, and two subcomponents of hyaluronic acid. Synovial fluid scavenging effect is enhanced in rheumatoid arthritis patients. Arthritis & RheumatismJan 1997; 31(1): 63-71.
Ialenti A and Di Rosa M. Hyaluronic acid modulates acute and chronic inflammation. Inflammation Research Volume 43, Numbers 1-2, 44-47.
Costagliola M, Agrosi M. Second-degree burns: a comparative, multicenter, randomized trial of hyaluronic acid plus silver sulfadiazine vs. silver sulfadiazine alone. Curr Med Res Opin. 2005 Aug; 21(8):1235-40.
Kramer MW, Escudero DO, Lokeshwar SD, Golshani R, Ekwenna OO, Acosta K, Merseburger AS, Soloway M, Lokeshwar VB. Association of hyaluronic acid family members (HAS1, HAS2, and HYAL-1) with bladder cancer diagnosis and prognosis. Cancer. 2011 Mar 15;117(6):1197-209. doi: 10.1002/cncr.25565. Epub 2010 Oct 19.