PC Samento

BioPure PC Samento


Tincture from Tropical vine to support immune system & antioxidant processes


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BioPure PC Samento made from natural Samento – Uncaria tomentosa – extract offered in a 1 fl oz tincture with dropper.

Samento (also known as Uncaria tomentosa, or Cat’s Claw) is derived from the bark of a tropical woody vine adorned with cat claw-like thorns. A sacred plant among the indigenous Amazonian tribes of Peru, it was believed to regulate both the physical and spiritual worlds, and was traditionally used for all sorts of ailments.

BioPure PC Samento contains numerous bioactive chemical compounds with beneficial health effects. Most potent are its POAs, or pentacyclic oxindole alkaloids, that have been shown to support the immune system.* Samento also has antioxidant effects.*

BioPure’s PC-Samento is guaranteed to be 100% free of tetracyclic oxindole alkaloids, (TOAs). It is a standardized herb containing a minimum of 0.5% pentacyclic oxindole alkaloids (POAs).


Research & More Information

PC-Samento is BioPure’s trade name for a derivative of the bark of a particular woody vine commonly called “Cat’s Claw”. The Cat’s Claw liana is native to the rainforests of Central and South America, where it can be found using its sharp cat-claw-shaped thorns to climb the trunks of trees toward the sunlight of the forest canopy. There are more than a dozen species of Cat’s Claw, but it is specifically Uncaria tomentosa that is used in PC-Samento because of its unique health benefits.

Historical records indicate Cat’s Claw, locally referred to as “Uña de Gato” or “Vilcacora”, has had religious, as well as medicinal significance for the indigenous people of Peru for at least 2000 years. The Anashninka tribe in Central Peru believed that “good spirits” inhabiting the plant were responsible for its beneficial properties. They have used Uña de Gato to treat all sorts of ailments, including digestive problems, infections, bone pain, inflammation, childbirth complications, and fevers.

Cat’s Claw received official recognition by the rest of the world in May of 1994, when the World Health Organization sponsored the First International Conference on Cat’s Claw in Geneva, Switzerland. Since then, numerous studies have been carried out investigating its chemical components.

Two compounds in Uncaria tomentosa that are of particular interest are tetracyclic oxindole alkaloids (TOAs) that act upon the central nervous system, and pentacyclic oxindole alkaloids (POAs) that act upon the immune system. The major weapons of our immune system in fighting illness are various types of specialized white blood cells that detect and attack abnormal cells, engulf and digest bacteria and foreign microbes, and produce antibodies to disease. The POAs in Uncaria tomentosa support the normal health and function of white blood cells.*

Interestingly, it has also been discovered that the TOAs present in some Cat’s Claw will actually cancel out the beneficial effects of the POAs. Therefore, BioPure Healing Products sells only a specific chemotype of Cat’s Claw, that is guaranteed to be 100% free of TOAs, and contains a minimum of 0.5% POAs. It is the unhindered action of these POAs that give our PC-Samento its unique properties. In addition, our extraction process uses just water and organic corn alcohol, and does not damage important plant proteins, ensuring that you receive a full spectrum of the plant’s health benefits.

Uncaria tomentosa extract has also been found to have antioxidant properties.* It is a source of flavonoid compounds called proanthocyanidins, as well as several quinovic acid glycolates.


Klaus Keplinger, Gerhard Laus, Martin Wurm, Manfred P. Dierich, Herwig Teppner. Uncaria tomentosa (Willd.) DC.–Ethnomedicinal use and new pharmacological, toxicological and botanical results. Journal of Ethnopharmacology 64 (1999) 23-34.

Karl-Heinz Reinhard. Uncaria tomentosa (Willd.) D.C.: Cat’s Claw, Uña de Gato, or Savéntaro. Journal of Alternative and Complementary Medicine April 1999, 5(2): 143-151.

Irma Lemaire, Valerie Assinewe, Pablo Cano, Dennis V.C. Awang and J. Thor Arnason. Stimulation of interleukin-1 and -6 production in alveolar macrophages by the neotropical liana, Uncaria tomentosa (Uña de Gato). Journal of Ethnopharmacology, Volume 64, Issue 2, 1 February 1999, Pages 109-115.

Iria Farias, Maria do Carmo Araújo, Estevan Sonego Zimmermann, Sergio Luiz Dalmora, Aloisio Luiz Benedetti, Marcio Alvarez-Silva, Ana Carolina Cavazzin Asbahr, Gustavo Bertol, Júlia Farias, Maria Rosa Chitolina Schetinger. Uncaria tomentosa stimulates the proliferation of myeloid progenitor cells. Journal of Ethnopharmacology. Volume 137, Issue 1, 1 September 2011, Pages 856–863.

Gonçalves C, Dinis TBatista MT. Antioxidant properties of proanthocyanidins of Uncaria tomentosa bark decoction: a mechanism for anti-inflammatory activity. Phytochemistry. 2005 Jan;66(1):89-98.