Curcumin found in BioPure CurcuSyn is a powerful polyphenol present in the spice turmeric used in traditional medicine with remarkable multiple health benefits. BioPure’s proprietary blend of ingredients in CurcuSyn® synergistically enhances absorption and bio availability for extended retention of curcumin in the blood for as long as 8-12 hours.
CurcuSyn® confers antioxidant properties and may be used to promote detoxification and immune system modulation.* It has been found to support gastrointestinal, liver, and blood metabolism, as well as balanced support for the body’s natural immune response.*
Research & More Information
CurcuSyn® is a blend of ingredients featuring curcumin as the primary bioactive. Curcumin is obtained from the roots of Curcuma longa, an herb in the ginger family, which when dried and powdered gives us the popular yellow Indian spice known as turmeric. Turmeric is one of the major ingredients in Indian curries, and has been an important substance in Chinese and Ayurvedic traditional medicines. It has been used to support a variety of bodily systems, including skin health, cardiovascular health, and digestive health to name a few.* Research has identified Curcumin as Turmeric’s primary bioactive compound and revealed that this natural phenol has antioxidant properties.
Early studies indicated that Curcumin was poorly absorbed in the human body, limiting access to its potential health benefits. However, new research has been discovering ways to increase absorption. BioPure’s CurcuSyn® is a proprietary formula of 100% natural, all vegetarian ingredients that synergistically work together to enhance absorption and bioavailability of Curcuma longa’s beneficial curcuminoids and sesquiterpenoids, and extend retention time of Curcumin in the blood for as long as 8-12 hours. As with all of our products, each ingredient is carefully crafted to provide you with the utmost in purity, potency and safety, and formulated for maximum effectiveness.
Because Curcumin has been found to confer antioxidant properties a number of different ways, the substance has been referred to as “Indian Solid Gold”, and is attracting a generous amount of scientific investigation. It supports cardiovascular health and proper lipid metabolism.* In vivo experiments with rodents have shown Curcumin may support healthy liver and nervous system function.* It is an immune system modulator and can help promote detoxification.* Clinical trials with humans indicate that Curcumin may help support normal blood sugar levels.*
Chattopadhyay I, Biswas K, Bandyopadhyay U and Banerjee RK. Turmeric and curcumin: Biological actions and medicinal applications. Current Science. Vol 87, No. 1, 10 July 2004.
Maheshwari RK, Singh AK, Gaddipati J, Srimal R. Multiple biological activities of curcumin: A short review. Life Sciences 78 (2006) 2081–2087.
Biswas SK, McClure D, Jimenez LA, Megson IL, Rahman I. Curcumin induces glutathione biosynthesis and inhibits NF-kappaB activation and interleukin-8 release in alveolar epithelial cells: mechanism of free radical scavenging activity. Antioxid Redox Signal. 2005 Jan-Feb;7(1-2):32-41.
Jurenka JS. Anti-inflammatory Properties of Curcumin, a Major Constituent of Curcuma longa: A Review of Preclinical and Clinical Research. Alternative Medicine Review. Volume 14, Number 2 2009, Pg 141-153.
Somlak Chuengsamarn, Suthee Rattanamongkolgul, Rataya Luechapudiporn, Chada Phisalaphong, and Siwanon Jirawatnotai. Curcumin Extract for Prevention of Type 2 Diabetes. Diabetes Care November 2012 vol. 35 no. 11 2121-2127.
Bo Wahlström, G. Blennow. A Study on the Fate of Curcumin in the Rat. Acta Pharmacologica et Toxicologica. Volume 43, Issue 2, pages 86–92, August 1978.
Preetha Anand, Sherin G. Thomas, Ajaikumar B. Kunnumakkara, Chitra Sundaram, Kuzhuvelil B. Harikumar, Bokyung Sung, Sheeja T. Tharakan, Krishna Misra, Indira K. Priyadarsini, Kallikat N. Rajasekharan, Bharat B. Aggarwal. Biological activities of curcumin and its analogues (Congeners) made by man and Mother Nature. Biochemical Pharmacology. Volume 76, Issue 11, 1 December 2008, Pages 1590–1611.
Zhou H, Beevers CS, Huang S. The targets of curcumin. Curr Drug Targets. 2011 Mar 1;12(3):332-47.
Aggarwal BB, Sundaram C, Malani N, Ichikawa H. Curcumin: the Indian solid gold. Adv Exp Med Biol. 2007;595:1-75.
Shen C-L, Smith BJ, Lo D-F, Ming-Chien Chyu M-C, Dunn DM, Chen C-H, Kwun I-S. Dietary polyphenols and mechanisms of osteoarthritis. Journal of Nutritional Biochemistry 23 (2012) 1367–1377.
Kuptniratsaikul V, Thanakhumtorn S, Chinswangwatanakul P, Wattanamongkonsil L, Thamlikitkul V. Efficacy and safety of Curcuma domestica extracts in patients with knee osteoarthritis. J Altern Complement Med. 2009 Aug;15(8):891-7.
Chandran B, Goel A. A Randomized, Pilot Study to Assess the Efficacy and Safety of Curcumin in Patients with Active Rheumatoid Arthritis. Phytotherapy Research. Volume 26, Issue 11, pages 1719–1725, November 2012.
Krishnaswamy K. Traditional Indian spices and their health significance. Asia Pac J Clin Nutr. 2008;17 Suppl 1:265-8.
Singh R, Sharma P. Hepatoprotective Effect of Curcumin on Lindane-induced Oxidative Stress in Male Wistar Rats. Toxicol Int. 2011 Jul;18(2):124-9.
Mahuya Sengupta, Gauri Dutta Sharma, Biswajit Chakraborty. Hepatoprotective and immunomodulatory properties of aqueous extract of Curcuma longa in carbon tetra chloride intoxicated Swiss albino mice. Asian Pacific Journal of Tropical Biomedicine (2011)193-199.
Jun Jiang, Wei Wang, Yong Jun Sun, Mei Hu, Fei Li, Dong Ya Zhu. Neuroprotective effect of curcumin on focal cerebral ischemic rats by preventing blood–brain barrier damage. European Journal of Pharmacology. Volume 561, Issues 1–3, 30 April 2007, Pages 54–62.
Cole GM, Teter B, Frautschy SA. Neuroprotective effects of curcumin. Adv Exp Med Biol. 2007;595:197-212.
Sethi P, Jyoti A, Hussain E, Sharma D. Curcumin attenuates aluminium-induced functional neurotoxicity in rats. Pharmacol Biochem Behav. 2009 Jul;93(1):31-9.
Jagetia GC, Aggarwal BB. “Spicing up” of the immune system by curcumin. J Clin Immunol. 2007 Jan;27(1):19-35. Epub 2007 Jan 9.
Xu Y, Ku BS, Yao HY, Lin YH, Ma X, Zhang YH, Li XJ. Antidepressant effects of curcumin in the forced swim test and olfactory bulbectomy models of depression in rats. Pharmacol Biochem Behav. 2005 Sep;82(1):200-6.
S.K. Kulkarni, Ashish Dhir, and Kiran Kumar Akula. Potentials of Curcumin as an Antidepressant. The Scientific World Journal (2009) 9, 1233–1241.
Hussan F, Ibraheem NG, Kamarudin TA, Shuid AN, Soelaiman IN, and Othman F. Curcumin Protects against Ovariectomy-Induced Bone Changes in Rat Model. Evidence-Based Complementary and Alternative Medicine, Volume 2012.
Wickenberg J, Ingemansson SL, Hlebowicz J. Effects of Curcuma longa (turmeric) on postprandial plasma glucose and insulin in healthy subjects. Nutr J. 2010 Oct 12;9:43.
Mohandas KM, Desai DC. Epidemiology of digestive tract cancers in India. V. Large and small bowel. Indian J Gastroenterol. 1999 Jul-Sep;18(3):118-21.
Johnson JJ, Mukhtar H. Curcumin for chemoprevention of colon cancer. Cancer Lett. 2007 Oct 8;255(2):170-81.
Aggarwal BB, Kumar A, Bharti AC. Anticancer potential of curcumin: preclinical and clinical studies. Anticancer Res. 2003 Jan-Feb;23(1A):363-98.
Gaurisankar Sa and Tanya Das. Anti cancer effects of curcumin: cycle of life and death. Cell Division 2008, 3:14.