Baikalin Powder

BioPure

$37.00

SKU: 599 Category:

BioPure’s Baikalin is a powdered extract from the root of Scutellaria baicalensis, also known as Chinese Skullcap, Huang-Qin, or Baikal Skullcap. This herb is in the Lamiaceae (mint) family and gets its name from its blue to purplish-pink flowers that have a shape resembling a medieval knight’s helmet. The Chinese have used Scutellaria in traditional medicine for over 2000 years. In Ayurvedic medicine, Scutellaria is considered a cooling herb.

Baicalin, and its close relative, baicalein, are the primary bioactive flavonoid compounds found in the roots of Scutellaria baicalensis. Baicalin has been shown to offer various pharmacological effects in research, including protection against free radical damage, inflammation modulating, neuroprotective, and immune system support. Of particular interest is Baicalin’s beneficial effects on the central nervous system, which has promising development in research on neurodegeneration, compulsive behavior, nervousness, and low mood.

Baicalin has a unique ability to penetrate the blood-brain barrier, and thus can facilitate targeted delivery of neuroprotective effects to the brain. Additional effects studied with promising results include increasing blood circulation, reducing the rate of mutation in cells, calming the nervous system, protecting chondrocytes, and memory-enhancing.

Studies have shown baicalin strengthening our body’s natural defenses against harmful invaders by interfering with the interactions of cell envelope proteins. In this way, it disrupts the binding and reception process that retroviruses use to gain access to a host’s cells. Dr. Dietrich Klinghardt, MD, PhD, and Dr. Judy Mikovits, PhD, believe retroviruses may be the driving force behind symptoms of many chronic illnesses. BioPure’s new Baikalin Powder, derived from the roots of Scutellaria baicalensis, was formulated with this approach and these various health benefits in mind.

References

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Dou J, Wang Z, Ma L, Peng B, Mao K, Li C, Su M, Zhou C, Peng G. Baicalein and baicalin inhibit colon cancer using two distinct fashions of apoptosis and senescence. Oncotarget. 2018 Jan 8;9(28):20089-20102.

Gasiorowski K, Lamer-Zarawska E, Leszek J, Parvathaneni K, Yendluri BB, Błach-Olszewska Z, Aliev G. Flavones from root of Scutellaria baicalensis Georgi: drugs of the future in neurodegeneration? CNS Neurol Disord Drug Targets. 2011 Mar;10(2):184-91.

Jia Y, Xu R, Hu Y, Zhu T, Ma T, Wu H, Hu L. Anti-NDV activity of baicalin from a traditional Chinese medicine in vitro. J Vet Med Sci. 2016 Jun 1;78(5):819-24.

Kim EH, Shim B, Kang S, Jeong G, Lee JS, Yu YB, Chun M. Anti-inflammatory effects of Scutellaria baicalensis extract via suppression of immune modulators and MAP kinase signaling molecules. J Ethnopharmacol. 2009 Nov 12;126(2):320-31.

Kudo M, Kobayashi-Nakamure K, Tsuji-Naito K. Bifunctional effects of O-methylated flavones from Scutellaria baicalensis Georgi on melanocytes: Inhibition of melanin production and intracellular melanosome transport. PLoS ONE 12(2): e0171513.

Lamer-Zarawska E, Wisniewska A, Blach-Olszewska Z. Anticancer Properties of Scutellaria baicalensis Root in Aspect of Innate Immunity Regulation. Adv Clin Exp Med 2010, 19, 4, 419-428.

Li BQ, Fu T, Dongyan Y, Mikovits JA, Ruscetti FW, Wang JM. Flavonoid baicalin inhibits HIV-1 infection at the level of viral entry. Biochem Biophys Res Commun. 2000 Sep 24;276(2):534-8.

Li C, Lin G, Zuo Z. Pharmacological effects and pharmacokinetics properties of Radix Scutellariae and its bioactive flavones. Biopharm Drug Dispos. 2011 Nov;32(8):427-45.

Li K,  Yao F,  Xue Q, Fan H, Yang L, Li X, Sun L, and Liu Y. Inhibitory effects against α-glucosidase and α-amylase of the flavonoids-rich extract from Scutellaria baicalensis shoots and interpretation of structure–activity relationship of its eight flavonoids by a refined assign-score method. Chem Cent J. 2018; 12: 82.

Liang W, Huang X, Chen W. The Effects of Baicalin and Baicalein on Cerebral Ischemia: A Review. Aging Dis. 2017 Dec 1;8(6):850-867.

Lin LT,  Hsu WC, and Lin CC. Antiviral Natural Products and Herbal Medicines. J Tradit Complement Med. 2014 Jan-Mar; 4(1):24-35.

Shi H, Ren K, Lv B, Zhang W, Zhao Y, Tan RX, and Li E. Baicalin from Scutellaria baicalensis blocks respiratory syncytial virus (RSV) infection and reduces inflammatory cell infiltration and lung injury in mice. Sci. Rep. 6, 35851; (2016).

Sowndhararajan K,  Deepa P,  Kim M,  Park SJ, and   Kim S. Neuroprotective and Cognitive Enhancement Potentials of Baicalin: A Review. Brain Sci. 2018 Jun; 8(6): 104.

Wu X, Zhi F, Lun W, Deng Q, Zhang W. Baicalin inhibits PDGF-BB-induced hepatic stellate cell proliferation, apoptosis, invasion, migration and activation via the miR-3595/ACSL4 axis. Int J Mol Med. 2018 Apr;41(4):1992-2002.

Zhao Q, Zhang Y, Wang G, Hill L, Weng JK, Chen XY, Xue H, Martin C. A specialized flavone biosynthetic pathway has evolved in the medicinal plant, Scutellaria baicalensis. Sci. Adv 2016;2:e1501780 8 April 2016

Zhou HC, Du R, Wang H, Zeng FL, Shi K, Li JM, Zong Y. Advance in studies on pharmacokinetics of baicalin. Zhongguo Zhong Yao Za Zhi. 2018 Feb;43(4):684-688.