Andrographis

BioPure

Tincture of South Asian herb Andrographis for immune system support

$40.00

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Andrographis paniculata, also known as King of Bitters or kalmegh, is an annual shrub in the family Acanthaceae. The plant is native to India and Sri Lanka and has been used throughout Southeast Asia and China for centuries.

Its applications span a variety of uses including immune system, lung, blood sugar, and menstrual support. In Thailand, the Ministry of Public Health recognizes Andrographis as an important herbal ally and it’s used in both hospitals and public health services. It is also viewed as being equally important in India where it is prominent in as many as 26 different Ayurvedic formulas.The major health benefits of Andrographis are its liver protecting, inflammation modulating, and immune supporting properties.* Analysis of histological studies and liver protein content showed Andrographis could provide a significant protective effect on mice livers.* These findings support the fact that Indian traditional medicine has long used the herb for its strong affinity to the liver.*

All parts of the Andrographis plant have been used to extract useful bioactives, but the dominant phytochemicals are isolated from the aerial parts of the plant, and comprise a group of labdane diterpenes known as Andrographolides. These compounds are attributed with most of the herb’s beneficial properties, including inflammation modulating, and liver and immune system support.* Andrographolide compounds may also be useful in supporting cardiovascular health by having an inhibitory effect on platelet aggregation.*

BioPure’s Andrographis is an herbal extract in a 33 percent organic corn alcohol solution, with purified water. It comes from the aerial parts of the plant, where most of the bioactive phytochemicals are found. Andrographis is reported to be very safe when used as recommended.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

 

References:

Awang K, Abdullah NH, Hadi AHA, Fong YS. Cardiovascular Activity of Labdane Diterpenes from Andrographis paniculata in Isolated Rat Hearts. Journal of Biomedicine and Biotechnology. Vol 2012, Article ID 876458, 5pgs.

Chua LS. Review on liver inflammation and antiinflammatory activity of Andrographis paniculata for hepatoprotection. Phytother Res. 2014 Nov;28(11):1589-98.

Churiyah, Pongtularan OB, Rofaani E, Tarwadi. Antiviral and Immunostimulant Activities of Andrographis paniculata. Hayati Journal of Biosciences. April 2015. Vol. 22, No. 2, p 67-72.

Devaraj S, Jegathambigai R, Kumar P, Sivaramakrishnan S. A Study on the Hepatoprotective Effect of Andrographis paniculata (Bur.F) Nees on Mice. Journal of Phytology 2010, 2(11): 25-30.

Dey YN, Kumari S, Ota S, Srikanth N. Phytopharmacological review of Andrographis paniculata (Burm.f) Wall. ex Nees. International Journal of Nutrition, Pharmacology, Neurological Diseases. 2013. Vol 3(Issue 1), Pgs 3-10.

Hidalgo MA, Hancke JL, Bertoglio JC, and Burgos RA. Andrographolide a New Potential Drug for the Long Term Treatment of Rheumatoid Arthritis Disease. 2013. In: Innovative Rheumatology, 1st Edition, Chapter 11:256-279. Published by InTech, Rijeka, Croatia.

Jarukamjorn K and Nemoto N. Pharmacological Aspects of Andrographis paniculata on Health and Its Major Diterpenoid Constituent Andrographolide. 2008. Journal of Health Science, 54(4) 370-381.

Jayakumar T, Hsieh CY, Lee JJ, Sheu JR. Experimental and Clinical Pharmacology of Andrographis paniculata and Its Major Bioactive Phytoconstituent Andrographolide. Evidence-Based Complementary and Alternative Medicine. Vol  2013, Article ID 846740, 16 pgs.

Nagalekshmi R, Menon A, Chandrasekharan DK, Nair CK. Hepatoprotective activity of Andrographis paniculata and Swertia chirayita. Food Chem Toxicol. 2011 Dec;49(12):3367-73.

Okhuarobo A, Falodun JE, Erharuyi O, Imieje V, Falodun A, and Langer P. Harnessing the medicinal properties of Andrographis paniculata for diseases and beyond: a review of its phytochemistry and pharmacology. Asian Pac J Trop Dis. 2014 Jun; 4(3): 213–222.

Priengprom T, Ekalaksananan T, Kongyingyoes B, Suebsasana S, Aromdee C, Pientong C. Synergistic effects of acyclovir and 3, 19- isopropylideneandrographolide on herpes simplex virus wild types and drug-resistant strains. BMC Complement Altern Med. 2015; 15: 56.

Tang LI, Ling AP, Koh RY, Chye SM, Voon KG. Screening of anti-dengue activity in methanolic extracts of medicinal plants. BMC Complement Altern Med. 2012 Jan 13;12:3.

Thisoda P, Rangkadilok N, Pholphana N, Worasuttayangkurn L, Ruchirawat S, Satayavivad J. Inhibitory effect of Andrographis paniculata extract and its active diterpenoids on platelet aggregation. Eur J Pharmacol. 2006 Dec 28;553(1-3):39-45.

Yarnell E, and Abascal K. Herbal Medicine for Viral Hepatitis. Alternative and complimentary Therapies. Mary Ann Liebert, Inc. Vol 16, No 3, June 2010.

Yoopan N, Thisoda P, Rangkadilok N, Sahasitiwat S, Pholphana N, Ruchirawat S, Satayavivad J. Cardiovascular effects of 14-deoxy-11,12-didehydroandrographolide and Andrographis paniculata extracts. Planta Med. 2007 Jun;73(6):503-11.

Zou W, Xiao Z, Wen X, Luo J, Chen S, Cheng Z, Xiang D, Hu J, He J. The anti-inflammatory effect of Andrographis paniculata (Burm. f.) Nees on pelvic inflammatory disease in rats through down-regulation of the NF-κB pathway. BMC Complement Altern Med. 2016 Nov 25;16(1):483.